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| STARTERS AVG AB R H HR RBI |
| Catcher |
| Torrealba, Col .255 396 47 101 8 47 |
| Varitek, Bos .255 435 57 111 17 68 |
| First Base |
| Helton, Col .320 557 86 178 17 91 |
| Youkilis, Bos .288 528 85 152 16 83 |
| Second Base |
| Matsui, Col .288 410 84 118 4 37 |
| Pedroia, Bos .317 520 86 165 8 50 |
| Third Base |
| Atkins, Col .301 605 83 182 25 111 |
| Lowell, Bos .324 589 79 191 21 120 |
| Shortstop |
| Tulowitzki, Col .291 609 104 177 24 99 |
| Lugo, Bos .237 570 71 135 8 73 |
| Outfield |
| Holliday, Col .340 636 120 216 36 137 |
| Taveras, Col .320 372 64 119 2 24 |
| Hawpe, Col .291 516 80 150 29 116 |
| Ramirez, Bos .296 483 84 143 20 88 |
| Crisp, Bos .268 526 85 141 6 60 |
| Drew, Bos .270 466 84 126 11 64 |
| Designated Hitter |
| Ortiz, Bos .332 549 116 182 35 117 |
| Spilborghs, Col .299 264 40 79 11 51 |
| RESERVES |
| Infielders |
| Carroll, Col .225 227 45 51 2 22 |
| Cora, Bos .246 207 30 51 3 18 |
| Hinske, Bos .204 186 25 38 6 21 |
| Outfielders |
| Baker, Col .222 144 17 32 4 12 |
| Smith, Col .625 8 4 5 0 0 |
| Sullivan, Col .286 140 19 40 2 14 |
| Ellsbury, Bos .353 116 20 41 3 18 |
| Kielty, Bos .218 87 10 19 1 12 |
| Catcher |
| Iannetta, Col .218 197 22 43 4 27 |
| Mirabelli, Bos .202 114 9 23 5 16 |
| Pitchers |
| W L ERA SV BB SO |
| Corpas, Col 4 2 2.08 19 20 58 |
| Herges, Col 5 1 2.96 0 15 30 |
| Fuentes, Col 3 5 3.08 20 23 56 |
| Hawkins, Col 2 5 3.42 0 16 29 |
| Morales, Col 3 2 3.43 0 14 26 |
| Affeldt, Col 4 3 3.51 0 33 46 |
| Speier, Col 3 1 4.00 0 8 13 |
| Cook, Col 8 7 4.12 0 44 61 |
| Francis, Col 17 9 4.22 0 63 165 |
| Jimenez, Col 4 4 4.28 0 37 68 |
| Fogg, Col 10 9 4.94 0 59 94 |
| Papelbon, Bos 1 3 1.85 37 15 84 |
| Delcarmen, Bos 0 0 2.05 1 17 41 |
| Okajima, Bos 3 2 2.22 5 17 63 |
| Lopez, Bos 2 1 3.10 0 18 26 |
| Beckett, Bos 20 7 3.27 0 40 194 |
| Timlin, Bos 2 1 3.42 1 14 31 |
| Gagne, Bos 4 2 3.81 16 21 51 |
| Snyder, Bos 2 3 3.81 0 32 41 |
| Schilling, Bos 9 8 3.87 0 23 101 |
| Matsuzaka, Bos 15 12 4.40 0 80 201 |
| Lester, Bos 4 0 4.57 0 31 50 |
