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JACKSON, Miss. — An extremely rare infection has been passed from an organ donor to at least one recipient in what is thought to be the first human-to-human transfer of the amoeba, medical officials said Friday.

Four people in three states received organs from a patient who died at the University of Mississippi Medical Center in November after suffering from neurological problems, said Dave Daigle, spokesman for the Centers for Disease Controls and Prevention.

Two of the recipients are critically ill, but the others haven’t shown symptoms, Daigle said. The CDC confirmed the presence of the organism, known as Balamuthia mandrillaris, in one recipient.

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