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Mixing alcohol and caffeine is hardly a new concept, but a rash of cases involving students and others who landed at hospitals after drinking beverages that combine the two in a single large can has alarmed college and health officials. The drinks are dangerous, doctors say, because the caffeine masks the effects of the alcohol, keeping consumers from realizing just how intoxicated they are.

A brand called Four Loko, a fruit-flavored malt beverage that has an alcohol content of 12 percent and as much caffeine as a cup of coffee, has come under scrutiny after students who drank it this fall at Ramapo College in Mahwah, N.J., and Central Washington University in Ellensburg, Wash., ended up in emergency rooms, some with high levels of alcohol poisoning.

At the urging of 18 attorneys general, the Food and Drug Administration, which has never approved adding caffeine to alcohol, is reviewing whether the drinks are safe. The New York Times

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