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MIAMI — In the biggest such study to date, research institutions have identified four genes implicated in causing Alzheimer’s disease.
While only five or six of as many as 100 genes linked to Alzheimer’s are now known, the development signals a “monumental breakthrough” that could lead to identification of nearly all the suspect genes in three to five years, said Dr. Margaret Pericak- Vance, who led analysis of the genes for the University of Miami’s medical school. The breakthrough could lead to better-targeted medicines and lifestyle changes to fight Alzheimer’s, researchers said.
The results, a collaboration of investigators from 44 universities and institutions, appear in this month’s Nature Genetics.



