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LOS ANGELES — A medical examiner, striking a major blow to the defense of Michael Jackson’s doctor, said Tuesday it is unreasonable to believe Jackson could have given himself a fatal dose of the powerful anesthetic propofol.

Dr. Christopher Rogers, who conducted the autopsy on Jackson, testified it was more likely that Dr. Conrad Murray overdosed the singer when he incorrectly estimated how much of the drug he was giving Jackson to induce sleep.

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