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SHANGHAI — A Zimbabwe-registered cargo plane crashed in flames during takeoff from Shanghai’s main airport Saturday, killing three American crew members and injuring four others on board. The accident closed two runways at the Pudong airport in China’s largest city for several hours.

The MD-11 cargo plane, operated by Zimbabwe-based Avient Aviation, was heading to Bishkek, the capital of Kyrgyzstan, said the official Xinhua News Agency.

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