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LAS VEGAS — Republican Sen. John Ensign of Nevada, damaged politically and facing a Senate ethics investigation over an extramarital affair, said Monday he won’t seek re-election next year.

Ensign, who is under investigation by the Senate Ethics Committee, said he decided last week against seeking a third term because he was worried about the effect of a campaign on his family.

“I’m putting them first, instead of my career,” Ensign said.

Ensign, 52, acknowledged in June 2009 that he had an extramarital affair with Cynthia Hampton, a former member of his campaign staff, and that he had helped her husband, Doug Hampton, a member of his congressional staff, obtain lobbying work with a Nevada company.