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In the instant before his surgically repaired left shoulder was crunched against the cold turf Sunday night, nearly everything else had already gone wrong for .

From a three-and-out on his first drive to the fumble he was fortunate to recover, to the body blows he absorbed on a chilly night at Sports Authority Field, there was nothing about Siemian’s game that resembled his performances that paced Denver to back-to-back to wins to open the season.

That fast start to the season had given the Broncos hope their second-year quarterback had turned a major corner. It was a stretch that seems long ago after Siemian failed to ignite the Broncos’ offense for the third time in as many games.

鈥淲hen you have three turnovers, it抖阴ap hard to say he played well,鈥� Broncos coach Vance Joseph said. 鈥淏ut turnovers are always tied to the quarterback.鈥�

Siemian agreed.

鈥淭he turnovers are the story of the game for us,鈥� he said. 鈥淚 thought the intensity was fine. We hurt ourselves. You鈥檙e already playing a good team. You can鈥檛 play against yourself as well.鈥�

The low point Sunday came as Siemian telegraphed a pass to that was easily snared by Giants cornerback Janoris Jenkins. At the end of Jenkins’ 43-yard pick-six path to the end zone, Siemian’s futile attempt at a tackle could do nothing to stop the avalanche during one of the worst games of his young career.

Siemian rolled on the grass in pain as the Giants celebrated fruits of a 23-10 upset few saw coming.

The Denver quarterback spent the last drive of the first half in the locker room after injuring his shoulder, giving way for one series to backup . Siemian returned in the second half, but nothing changed.

Siemian finished 29-of-50 for 376 yards, one touchdown, two turnovers and a 71.8 passer rating. Much of the yardage, a career-high total for Siemian, amounted to empty gains through the air as the Broncos chased a three-score deficit late in the game.

The pain on his face, both after he injured the shoulder and following each of the four sacks he absorbed, painted a better story of the quarterback’s nightmare night.

On his first drive, Siemian’s third-down pass to sailed off the mark. On the Broncos’ next series, Siemian had the ball poked out of his hands by New York pass rusher Jason Pierre-Paul. Siemian recovered the ball as it bounced back toward his hands, but the Broncos punted again.

An offense that had a bye week to work out the kinks after slogging through back-to-back 16-point performances was stuck in quicksand.

鈥淚t抖阴ap the NFL,” Fowler said. “You have to come out and execute.”

Somehow things only got worse. Early in the second quarter, Siemian forced a pass down the right sideline for Thomas — Denver’s lone offensive bright spot Sunday — who was blanketed by safety Landon Collins, a promising drive ending with an interception.

“I tried to anticipate ‘DT’ rolling in there,” Siemian said. “I threw it early and the guy made a play.”

The Broncos had appeared to weather Siemian’s miscues and the overall ineptitude of the offense as halftime neared. After a sluggish start, the Broncos’ defense seemed to right the ship, and Denver trailed just 10-3 and faced a second-and-10 at its own 38-yard line with 1 minutes, 6 seconds left until halftime. The score as it stood would have the Broncos in position to take a deep breath and restore order in the second half.

Then, as Siemian stared down Fowler, Jenkins lingered just behind the receiver. He jumped the route and sprinted toward the end zone, a play that ended in pain for Siemian.

“I tried to tackle the guy and, obviously, that’s not my specialty,” said Siemian, who suffered a minor sprain to the non-throwing shoulder but isn’t expected to miss any time. “I’m a little sore, but I’m fine.”

When tight end Jeff Hueremann snared a 13-yard touchdown pass from Siemian late in the fourth quarter, nearly half of the fans in attendance had already headed toward the exits.

They had seen enough.