GAME OF THE WEEK
Patriots at Jaguars, 2:25 p.m.
A rematch of last year’s AFC title game in which the Jaguars squandered a 20-10 road lead in the fourth quarter and were denied a first-ever trip to the Super Bowl. This time, the game is in steamy Jacksonville. But the combination of Jaguars running back Leonard Fournette’s hamstring injury and Patriots tight end Rob Gronkowski’s availability will give New England a solid road win.
Patriots 34, Jaguars 24.
Ryan’s record: 1-0.
LOCK OF THE WEEK
Lions at 49ers, 2:05 p.m.
Detroit figures to bounce back in some shape or form after last week’s 48-17 home loss to the New York Jets. But the Lions appear in disarray and their best won’t be enough as 5 1/2-point underdogs. A big game for San Francisco, which doesn’t want to fall to 0-2 with trips to Kansas City and the Los Angeles Chargers in Weeks 3-4.
49ers 42, Lions 20.
Ryan’s record: 0-1.
UPSET OF THE WEEK
Chiefs at Steelers, 11 a.m.
The Chiefs rolled last week as a three-point road underdog at the Chargers (won 38-28). Kansas City is getting five points against a Steelers team that committed six turnovers at Cleveland and tied the Browns. Quarterback Ben Roethlisberger has an elbow issue that kept him out of practice. The Chiefs make it two impressive road wins in a row.
Chiefs 29, Steelers 24.
Ryan’s record: 1-0.
