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NFL picks: Niners-Cowboys a terrific Sunday night matchup and Buffalo takes its scorching offense to London

Plus, the Lions get a weapon back and a former CU star deals with a long-running injury

San Francisco 49ers head coach Kyle Shanahan watches from the sideline during the second half of an NFL football game against the New York Giants in Santa Clara, Calif., Thursday, Sept. 21, 2023. (AP Photo/Godofredo A. Vásquez)
San Francisco 49ers head coach Kyle Shanahan watches from the sideline during the second half of an NFL football game against the New York Giants in Santa Clara, Calif., Thursday, Sept. 21, 2023. (AP Photo/Godofredo A. Vásquez)
Parker Gabriel - Staff portraits in The Denver Post studio on October 6, 2022. (Photo by Eric Lutzens/The Denver Post)
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Getting your player ready...
This look around Week 5 action in the NFL features the 49ers and Cowboys in a terrific Sunday night matchup, Buffalo taking its scoring offense to London and an All-Pro from CU dealing with yet more injury issues.
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