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PORT WENTWORTH, Ga. — An explosion and fire at a sprawling sugar refinery rattled this Savannah suburb Thursday night, severely injuring dozens of people and sending authorities into the nearby Savannah River to search for possible victims, officials said.

No deaths were immediately reported in the blast. Ninety-five to 100 people were believed to be working in the area of the blast, and six were unaccounted for, said Chief Michael Berkow of the Savannah-Chatham County police.

“As far as we know, it was a sugar dust explosion,” Imperial Sugar chief executive John Sheptor said. The blast happened in a silo where refined sugar is stored until it is packaged, he said.

At least 40 people were taken to hospitals, and eight of them were flown to a burn center in Augusta, 130 miles up the Savannah River, he said.

Nakishya Hill, a machine operator, said she escaped from the third floor of the refinery.

“All I know is, I heard a loud boom and everything came down,” said Hill, who was not injured except for blisters on her elbow. “When I got up, I went down and found a couple of people, and we climbed out of there from the third floor to the first floor. Half of the floor was gone. The second floor was debris; the first floor was debris.

“All I could do when I got down was take off running,” she said.

Dr. Jay Goldstein of Memorial University Medical Center said 30 to 35 patients were being treated, all in critical condition and most with “significant burns.” Candler Hospital reported three patients in serious condition.

Coast Guard Lt. Cmdr. Kevin Lynn said shipping was shut down on the Savannah River while the waterway was searched for potential victims.

The plant is a Savannah landmark. Imperial, based in Sugar Land, Texas, acquired Savannah Foods & Industries in 1997. Imperial markets some leading consumer brands — Imperial, Dixie Crystals and Holly.

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