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DAVOS, Switzerland — The leader of the $22.6 billion Global Fund to Fight AIDS, Tuberculosis and Malaria has abruptly resigned, part of a shakeup in its top management since revelations about corruption and misspending severely rattled some of its biggest donors.

Dr. Michel Kazatchkine, a French clinical immunologist who has served as executive director of the global health fund for the past five years, announced Tuesday that he will resign in March.

Denver Post wire services

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