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A man driving a pickup was shot and killed early Saturday, and the truck ultimately crashed into a Walgreens store under construction at South Federal Boulevard and West Alameda Avenue, according to Denver police.

Two passengers in the pickup were treated at Denver Health Medical Center for injuries that were not life-threatening. They have been released. The driver was pronounced dead at the scene.

After the shooting, the pickup hit the store’s wall and damaged a portable toilet.

Preliminary reports from the scene show the assailants may have fled in two separate cars.

But investigators were still trying to determine Saturday evening whether the victims were targeted or the shooting was random, said police spokeswoman Sharon Avendaño.

The assailants may have been driving a green sport utility vehicle and a black sedan, according to police. The shooting occurred just before 2 a.m.

The victims’ names have not been released.

Andy Vuong: 303-954-1209 or avuong@denverpost.com

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