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UNITED NATIONS — Delegates preparing for a major conference next year to review the Nuclear Nonproliferation Treaty have agreed on an agenda, and some said the change in President Barack Obama’s tone and emphasis was a key factor.

Obama’s pledge last month to reduce and eventually eliminate nuclear weapons — a major reversal from former President George W. Bush’s policy — has spurred hope that it and new U.S.-Russian cooperation will end a long deadlock on global-disarmament efforts.

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