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SALINA, N.Y. — A double-decker bus that might have made a wrong turn off the highway slammed into a low railroad bridge in the pre-dawn darkness Saturday in a wreck that killed four passengers and critically injured others, authorities said.

The Megabus was carrying 29 people, including the driver, when it rammed the bridge about 2:30 a.m. on the Onondaga Lake Parkway in Salina, a suburb of Syracuse, N.Y.

Three passengers and the driver remained hospitalized Saturday afternoon.

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