WASHINGTON — Sovaldi, a new pill for hepatitis C, cures the liver-wasting disease in nine of 10 patients, but treatment can cost more than $90,000. Leading medical societies recommend the drug as a first-line treatment, and patients are clamoring for it.
But insurance companies and state Medicaid programs are gagging on the price.
In Oregon, officials propose to limit how many low-income patients can get Sovaldi.
Yet if Sovaldi didn’t exist, insurers would still be paying in the mid- to high five figures to treat the most common kind of hepatitis C, a new pricing survey indicates. Some of the older alternatives involve more side effects and are less likely to provide cures.
The cost of this breakthrough drug is highlighting cracks in the U.S. health care system at a time of heightened budget concerns. The Obama administration has a huge political stake in controlling treatment costs, but its critics may cry rationing.
“People are going to want to try to dodge this hot potato,” economist Douglas Holtz-Eakin said.
For insurers, there’s a frustrating twist: For each middle-aged person they pay to cure with Sovaldi, any financial benefits from preventing liver failure are likely to accrue to Medicare, not to them.
More than 3 million Americans carry the hepatitis C virus, and many don’t realize it. The illness is complex, with distinct virus types requiring different treatments. While it progresses gradually, it ultimately can destroy the liver, and transplants average $577,000.
An estimated 15,000 people died from hepatitis C in the U.S. in 2007, when it surpassed AIDS as a cause of death.
Until the drug’s approval late last year, standard treatment for the most common type of the disease required daily pills and extended use of interferon, an injection that can produce debilitating flulike symptoms.
Taken once a day for 12 weeks, Sovaldi greatly reduces the length of interferon treatment, making things more tolerable for patients. Now, many more people might want to try the cure.
A similar drug, Olysio, also approved last year, is priced lower.
The nation’s largest care provider for chronic hepatitis C, the federal Veterans Administration, sees promise. With 175,000 patients, the VA has started more than 1,850 of them on Sovaldi.
“After 20 years in infectious diseases, I never thought we would be in a position to cure this disease,” said Dr. David Ross, head of the VA’s program.
By law, the VA gets drug discounts of more than 40 percent. Will the agency break even by avoiding the worst complications? Not necessarily, Ross said.
“If it leads to cost benefits in the long run, that’s gravy,” Ross said.



